To be added to food, this additive must achieve 99% purity. However, this leaves room for small amounts of potential contaminants like lead, arsenic, or mercury (1Trusted Source).
The factory's commitment to quality is evident in its production process, which adheres to strict standards and regulations. By using advanced technology and techniques, CAS 13463-67-7 is able to produce titanium dioxide that meets the exact specifications of its customers. This ensures that the final product is of the highest quality and consistency, leading to better performance and results for the end-users.
In addition to the toxic effects of TiO2 NPs, discussed in previous chapters, these NPs have been also shown to promote photosynthesis and nitrogen metabolism, resulting in the enhanced growth of spinach. It increases the absorption of light and accelerates the transfer and transformation of the light energy. It was also found that treatment with nano-sized TiO2 significantly increased the level of antioxidant enzymes, and decreased the ROS accumulation and malonyldialdehyde content in spinach chloroplasts under visible and UV irradiation. TiO2 NPs also increased the superoxide dismutase activity of germinating soybean, enhanced its antioxidant ability, and promoted seed germination and seedling growth.
Restraint
For a mini-review published in the journal Particle and Fibre Technology in 2021, scientists wanted to evaluate whether Ti02 particles contributed to the development and/or exacerbation of irritable bowel disease, and whether they altered the four elements of intestinal barrier function: the intestinal microbiota, the immune system, the mucus layer, and the epithelium. The breakdown of these four elements can contribute to autoimmune, neurological, inflammatory, infectious, and metabolic diseases. Following their review, the researchers concluded: “Data indicate that TiO2 is able to alter the four compartments of IBF and to induce a low-grade intestinal inflammation associated or not with pre-neoplastic lesions.”
Nanotoxicology
Avoiding exposure
Does It Cause Cancer?
JECFA also evaluated estimates of dietary exposure to titanium dioxide, estimating the maximum 95th percentile of exposure to be 10 mg/kg BW per day. Overall, considering the low oral absorption of titanium dioxide as a food additive, the committee reaffirmed the ADI “not specified” that was established at the 13th meeting.
pH-value
