The reaction liquid is filtered through plate and frame pressure to obtain lithopone in the form of a filter cake with a moisture content of no more than 45%. It is then roasted in a drying furnace to change the crystal form of lithopone, and is then pickled with sulfuric acid at a temperature of 80°C. Finally, it is washed with water, reinforced with colorants, filtered, dried and ground into powder.

A number of our toothpastes do not contain titanium dioxide, including some of our Signal products (Signal Bio, Signal Nature Element, Signal White System, Signal Kids (Baby & Junior), Signal White Now Detox, Signal Anti-Cavity), Love Beauty and Planet and Schmidt’s Naturals.

It is naturally opaque and bright, which makes it useful for use in paper, ceramics, rubber, textiles, paints, inks and cosmetics.It is also resistant to ultraviolet (UV) light, and is used widely in sunscreens and pigments that are likely to be exposed to UV light. It is used in a wide variety of personal care products, including color cosmetics such as eye shadow and blush, loose and pressed powders and in sunscreens.

Still, in 2016 Skittles publicly declared it would get rid of the chemical compound in its products, according to a press release at the time from the Center for Food Safety, which called the substance harmful and potentially poisonous. But the ingredient remains, according to the lawsuit, which alleges the candy company is misleading consumers by not having eliminated titanium dioxide.

Over the last several years, nanoparticles have come under scrutiny for adverse health effects. Nanoparticles are ultrafine particles between 1 to 100 nanometers in diameter. (To put this in perspective, the average human hair is around 80,000 nanometers thick.) Because of their size, which can be engineered and manipulated at the atomic or molecular level, nanoparticles exhibit unique physical, chemical, and biological properties. Titanium dioxide is one of the most commonly produced nanoparticles in the world.

The aim of this work was to examine particularly the Degussa P25 titanium dioxide nanoparticles (P25TiO₂NPs) because they are among the most employed ones in cosmetics. In fact, all kinds of titanium dioxide nanoparticles (TiO₂NPs) have gained widespread commercialization over recent decades. This white pigment (TiO₂NPs) is used in a broad range of applications, including food, personal care products (toothpaste, lotions, sunscreens, face creams), drugs, plastics, ceramics, and paints. The original source is abundant in Earth as a chemically inert amphoteric oxide, which is thermally stable, corrosion-resistant, and water-insoluble. This oxide is found in three different forms: rutile (the most stable and substantial form), brookite (rhombohedral), and anatase (tetragonal as rutile), of these, both rutile and anatase are of significant commercial importance in a wide range of applications [3]. Additionally, the nano-sized oxide exhibits interesting physical properties, one of them is the ability to act as semiconducting material under UV exposure. In fact, TiO₂NPs are the most well-known and useful photocatalytic material, because of their relatively low price and photo-stability [4]. Although, this photoactivity could also cause undesired molecular damage in biological tissues and needs to be urgently assessed, due to their worldwide use. However, not all nanosized titanium dioxide have the same behavior. In 2007, Rampaul A and Parkin I questioned: “whether the anatase/rutile crystal form of titanium dioxide with an organosilane or dimethicone coat, a common titania type identified in sunscreens, is appropriate to use in sunscreen lotions” [5]. They also suggested that with further study, other types of functionalized titanium dioxide could potentially be safer alternatives. Later, Damiani found that the anatase form of TiO₂NPs was the more photoactive one, and stated that it should be avoided for sunscreen formulations, in agreement with Barker and Branch (2008) [6,7].

After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body, Maged Younes, chair of the European Food Safety Authority's expert Panel on Food Additives and Flavourings, said in a May 2021 statement.

The Journal of the American Institute for Conservation (JAIC) is an international peer-reviewed periodical for the art conservation profession. The Journal publishes articles on treatment case studies, current issues, materials research, and technical analyses relating to the conservation and preservation of historic and cultural works. The topics encompass a broad range of specialties including architectural materials, archeological objects, books and paper, ethnographic materials, objects, paintings, photographic materials, sculpture, and wooden artifacts. Started as the Bulletin of the International Institute for Conservation-American Group (IIC-AG), in April 1961, the Journal matured into its current form in 1977. Since that time JAIC has become a repository for the core body of conservation information through its documentation of new materials, changing methods, and developing standards in the conservation profession. The four-color publication is distributed three times a year to AIC members and museum, library, and university subscribers.