La Vera Smoked Hot Paprika, also known as picante, is a Spanish paprika that has been smoked the traditional way – in a drying house, over oak wood, for a period of 10-15 days. The end result is a spice that exhibits a deep, dark earthy red color and mild, but noticeable, heat. This spice measures approximately 500 - 1,000 on the Scoville Heat Unit Scale. 

Cayenne comes from the cayenne pepper. These peppers are also part of the Capsicum annuum family, but they’re much hotter than the peppers used to make paprika (from 35,000 Scoville heat units and up).

When substituting, use common sense. Cayenne pepper is as much as 50 times hotter than sweet paprika, so a 1:1 substitution wouldn't work unless you want some heat—the right substitution, in this case, would be 1/3 of a teaspoon of cayenne per 1 teaspoon of paprika. Make an informed decision, but also use thorough recipes that might suggest reasonable substitutions.