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  • Titanium dioxide (TiO2) is considered as an inert and safe material and has been used in many applications for decades. However, with the development of nanotechnologies TiO2 nanoparticles, with numerous novel and useful properties, are increasingly manufactured and used. Therefore increased human and environmental exposure can be expected, which has put TiO2 nanoparticles under toxicological scrutiny. Mechanistic toxicological studies show that TiO2 nanoparticles predominantly cause adverse effects via induction of oxidative stress resulting in cell damage, genotoxicity, inflammation, immune response etc. The extent and type of damage strongly depends on physical and chemical characteristics of TiO2 nanoparticles, which govern their bioavailability and reactivity. Based on the experimental evidence from animal inhalation studies TiO2 nanoparticles are classified as “possible carcinogenic to humans” by the International Agency for Research on Cancer and as occupational carcinogen by the National Institute for Occupational Safety and Health. The studies on dermal exposure to TiO2 nanoparticles, which is in humans substantial through the use of sunscreens, generally indicate negligible transdermal penetration; however data are needed on long-term exposure and potential adverse effects of photo-oxidation products. Although TiO2 is permitted as an additive (E171) in food and pharmaceutical products we do not have reliable data on its absorption, distribution, excretion and toxicity on oral exposure. TiO2 may also enter environment, and while it exerts low acute toxicity to aquatic organisms, upon long-term exposure it induces a range of sub-lethal effects.

  • In addition to its protective qualities, R996 also helps improve the overall appearance of paintsuniversaluniversal type product tio2 pigment titanium dioxide paints r996. Its high opacity and excellent hiding power ensure that paint colors remain vibrant and true, even when applied over dark or uneven surfaces. This makes R996 a valuable tool for painters looking to achieve a professional finish.
  • The wholesale availability of titanium dioxide anatase TIO2 plays a pivotal role in driving down costs for manufacturers without compromising on quality. By purchasing this key ingredient in bulk, paint manufacturers can take advantage of economies of scale, thereby reducing raw material expenses significantly. This cost-effective approach allows them to produce paints at a lower price point, making them accessible to a broader market segment.
  • Lithopone B311

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  • However, other countries like the United States, Japan, and Germany also have notable lithopone producers. These companies, although operating on a smaller scale, often offer higher quality products with specialized grades tailored to specific industries. For instance, American company Huber Engineered Materials and German-based Merck KGaA are renowned for their high-performance lithopone products.
  • The pharmaceutical industry, for instance, utilizes Zinc Barium Sulphate in the formulation of tablets and capsules due to its ability to act as a filler or binder. It also finds use as an absorbent in medical applications. In the realm of paints and coatings, it serves as a, enhancing the durability and opacity of the final product.
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  • Titanium dioxide is a versatile and widely used white pigment that is commonly found in a variety of products, including paper. Its high refractive index and opacity make it an excellent choice for improving the brightness and coverage of paper products.
  • In 2023, the demand for titanium dioxide is expected to reach new heights. One of the main drivers of this growth is the cosmetics and personal care industry. Titanium dioxide is widely used in sunscreens, skin care products and cosmetics for its excellent UV protection properties and ability to provide a smooth surface. With growing awareness of the harmful effects of UV radiation, consumers are increasingly inclined to invest in products with sun protection. This trend is expected to drive the demand for titanium dioxide over the next few years.

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  • In addition to logistical challenges, importers must also keep up with changing quality standards and environmental regulations. Titanium dioxide is classified as a potential human carcinogen by the International Agency for Research on Cancer, and there is increasing pressure on importers to ensure that the material meets strict safety and environmental guidelines
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    titanium dioxide importers.
  • Titanium dioxide is a widely used colorant in various industries, such as cosmetics, food, and plastics. As a leading titanium dioxide manufacturer, we are dedicated to providing high-quality products to meet the demands of our customers.
  • US 1478347, Mitchell John L, Apparatus for calcining lithopone, published Dec 18, 1923, assigned to Mitchell John L
  • Talc and Titanium Dioxide A Perfect Match for Manufacturing Excellence
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  • The rapid method of synthesis described here is readily scalable to the proportions required in cosmetics manufacture.

  • When examining a lithopone pigment pricelist, one might notice that prices can vary significantly between different grades of lithopone. Generally, there are two main types Lithopone 28 and Lithopone 60, with the numbers denoting the percentage of zinc sulfide content. Lithopone 28, with a lower zinc sulfide content, is often more affordable compared to Lithopone 60, which offers superior whiteness and opacity. The choice between these grades depends largely on the specific requirements of the end application.


  • In 2022, a year after the EFSA recommended against the use of E171, the Food Standards Australia New Zealand (FSANZ) conducted its own reassessment of titanium dioxide as a food additive. The agency concluded that titanium dioxide was indeed safe to use as a food additive. The United Kingdom and Canada came to similar conclusions.

  • Customer sues Mars:Skittles are 'unsafe' for consumers, lawsuit charges, because they contain 'a known toxin' 

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