Scientists analyzed research that examined how titanium dioxide nanoparticles interact with the brain for a 2015 review published in Nanoscale Research Letters. The researchers wrote: “Once the TiO2 NPs are translocated into the central nervous system through [certain] pathways, they may accumulate in the brain regions. For their slow elimination rates, those NPs could remain in the brain zones for a long period, and the Ti contents would gradually increase with repeated exposure.” After reviewing dozens of studies, the scientists concluded: “Long-term or chronic exposure to TiO2 nanoparticles could potentially lead to the gradually increased Ti contents in the brain, which may eventually induce impairments on the neurons and glial cells and lead to CNS dysfunction as a consequence.”

Mars Wrigley, the company that makes Skittles, is being sued by a California man who claims the candy contains a known toxin that poses such a serious health risk that Skittles are unfit for human consumption.

Lithopone

Another important property of Chinese anatase titanium dioxide is its photocatalytic activity, which enables it to break down organic pollutants and harmful chemicals when exposed to light. This makes it an attractive choice for applications in environmental remediation, such as air and water purification systems. Additionally, its photocatalytic properties have also been studied for use in self-cleaning surfaces, such as windows and building facades, where it can help to reduce maintenance costs and keep surfaces looking clean.