I don't see the scientific evidence in the literature that would cause people any concern, said Kaminski.
In summary, the Food Directorate's position is that there is no conclusive scientific evidence that the food additive TiO2 is a concern for human health. This is based on a review of the available scientific data relevant to food uses of TiO2. However, we will continue to monitor the emerging science on the safety of TiO2 as a food additive and may revisit our position if new scientific information becomes available.
≥99.0
From studies deemed relevant, the experts found that titanium dioxide as a food additive is poorly absorbed by the gastrointestinal tract of mice and rats, with no adverse effects observed in short-term studies in rodents receiving titanium dioxide in their diets. No observed adverse effect levels (NOAELs) of 15,000 milligrams per kilogram of bodyweight (mg/kg BW) per day and 5,000 mg/kg BW per day—the highest doses tested—were established for mice and rats, respectively.
The RGB LED panel was built ad hoc for this purpose. Measures: 23.5 × 16.5 cm. Light Intensity: 19,500.10 lux. (43.33 W in 0.2 m2) when set to solar simulation. It does not produce temperature increases in the surroundings.
R-996:
Dongfang Titanium Industry R-5568 titanium dioxide with zinc salt stabilizer, zirconium, aluminum, silicon coating. It has the characteristics of high blue phase, easy dispersion, high weather resistance, high hiding power, low oil absorption, good system compatibility, and excellent processing rheology. It is a high-quality titanium dioxide for plastics. Dongfang Titanium R-5568 titanium dioxide is recommended to be widely used in polyolefin, PVC, ABS, PS and other color masterbatches, profiles, plates and pipes, and can also be used in leather color paste, oily paint and other industries.
For a mini-review published in the journal Particle and Fibre Technology in 2021, scientists wanted to evaluate whether Ti02 particles contributed to the development and/or exacerbation of irritable bowel disease, and whether they altered the four elements of intestinal barrier function: the intestinal microbiota, the immune system, the mucus layer, and the epithelium. The breakdown of these four elements can contribute to autoimmune, neurological, inflammatory, infectious, and metabolic diseases. Following their review, the researchers concluded: “Data indicate that TiO2 is able to alter the four compartments of IBF and to induce a low-grade intestinal inflammation associated or not with pre-neoplastic lesions.”
In their role as risk managers, the European Commission and Member States will now reflect on EFSA’s scientific advice and decide upon any appropriate regulatory measures or advice for consumers.
Asia
This article was written by Kamilah Guiden and reviewed by Megan Meyer, PhD.
Exposure routes are the pathways that allow ingredients to enter our bodies. Primary exposure routes include:
Titanium dioxide is a common pigment, and zinc oxide and magnesium oxide are common fillers in rubber base adhesives.