The ROS seemed to be endlessly produced by P25TiO₂NPs upon irradiation, since the values detected after 6 h are similar to the ones after 3 h. However, the amount of vitamin B2 in the surface of the NPs proved to be enough to decrease the ROS detected even after 6 h. Statistical analysis showed a significant difference between C and A. p < 0.05

The FDA's Code of Federal Regulations allows for the legal, regulated use of titanium dioxide in food products, under some restrictions.

On the other hand, the U.S. Food and Drug Administration (FDA) in their Final Administrative Order on Sunscreen Drug Products posted in September 2021 still accepts titanium dioxide up to 25% in the list of Generally Recognized As Safe and Effective (GRASE) in the main document, without further clarification on what kind or size of particles [9]. However, on page 24 (Sunscreen containing nanomaterials) FDA clearly “distinguish nanomaterials from other forms of these ingredients'' (zinc oxide and titanium dioxide) and ask for comments on “any particular nanomaterials that you believe should not be permitted for use in OTC sunscreen products”. To the best of our knowledge, this Agency did not ban the use of nanoparticulate titanium dioxide in any form, even though it is mentioned on page 34 that the anatase form is the more photoactive one, due to the lack of evidence with real sunscreens OTC (over the counter) in vivo. Moreover, other regulations in Latin America (MERCOSUR agreement, 2006) do not state clearly their position on the use of nanoparticulate TiO₂NPs [10].

No. The titanium dioxide we use in our toothpastes has been proven safe by health experts around the world. It is used in our toothpastes as a white colourant, in a non-nano form as defined by European regulations. It is an approved colourant in cosmetics, and we comply with all the regulations applicable to it.

In conclusion, the MBR9668 rutile titanium dioxide coating is a revolutionary product that enhances the quality, efficiency, and sustainability of coatings across various industries. As a leading supplier of this material, companies can provide clients with high-performance solutions that meet modern demands for durability and aesthetics. With its unique benefits and applications, MBR9668 stands out as a key component in the future of quality coatings, setting new standards in product performance and longevity.