But what does that really mean for you, your skin & your health

Titanium Dioxide is one of the two members of the elite sunscreen group called physical sunscreens (or inorganic sunscreens if you’re a science geek and want to be precise).

The following aspects have been covered in the lithopone manufacturing plant report:

A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO₂. However, these same effects were not seen when the same or higher doses of food-grade TiO₂ were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO₂ from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.

See also

Algaecidal effect of Lithopon: After 5 years of exposure to weathering in Alpen (Lower Rhine)  

Below 20% substitution, it is recommended to replace 1 kg of TiO2 with 1 kg of Lithopone.  

Health Canada's Food Directorate recently completed a “state of the science” report on titanium dioxide (TiO₂) as a food additive. Food-grade TiO₂ is a white powder made up of small particles that has been permitted in Canada and internationally for many years as a food additive to whiten or brighten foods. Food-grade TiO₂ has long been considered safe in Canada and in other countries when eaten as part of the diet.

Overall, the Food Directorate's comprehensive review of the available science of TiO₂ as a food additive showed:

In Europe, the downstream paints and coatings sector presented weak demand in front of the titanium dioxide manufacturers, and thus, the titanium dioxide price trend experienced a gradual decline in its trajectory. Additionally, the pressure of inflation and increasing bank interest rates lowered the spending appetite of consumers which had an adverse effect on the titanium dioxide price trends. Further, the export and import of titanium dioxide were also caught under the negative influence of the poor economic conditions of the market.

Relative to a lot of other things that people should be concerned about, titanium dioxide in my mind, is really low on the list. I would be more worried about some substitutes that people are using for titanium dioxide that don't have decades of research associated with it, said Westerhoff.

Lithopone B311